Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling

Oncolytic viruses selectively target and replicate in cancer cells, providing us with a unique tool with which to target and kill tumour cells. These viruses come from a diverse range of viral families including reovirus type 3 Dearing (RT3D), a non-pathogenic human double-stranded RNA oncolytic vir...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: McEntee, Gráinne, Kyula, Joan N., Mansfield, David, Smith, Henry, Wilkinson, Michelle, Gregory, Claire, Roulstone, Victoria, Coffey, Matt, Harrington, Kevin J.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217035/
https://ncbi.nlm.nih.gov/pubmed/27384486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10365
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