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Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling
Oncolytic viruses selectively target and replicate in cancer cells, providing us with a unique tool with which to target and kill tumour cells. These viruses come from a diverse range of viral families including reovirus type 3 Dearing (RT3D), a non-pathogenic human double-stranded RNA oncolytic vir...
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Udgivet i: | Oncotarget |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Impact Journals LLC
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217035/ https://ncbi.nlm.nih.gov/pubmed/27384486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10365 |
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