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Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma

Treatment of advanced cutaneous T-cell lymphomas (CTCL) is challenging because they are resistant to conventional chemotherapy. USP2 has been shown to promote resistance to chemotherapeutic agents in several cancer models. We show here USP2 is expressed in quiescent and activated T-cells and its exp...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wei, Tianling, Biskup, Edyta, Rahbek Gjerdrum, Lise Mette, Niazi, Omid, Ødum, Niels, Gniadecki, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217025/
https://ncbi.nlm.nih.gov/pubmed/27351221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10268
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