miR-122 Regulates p53/Akt Signalling and the Chemotherapy-Induced Apoptosis in Cutaneous T-Cell Lymphoma

Advanced cutaneous T-cell lymphoma (CTCL) is resistant to chemotherapy and presents a major area of medical need. In view of the known role of microRNAs (miRNAs) in the regulation of cellular signalling, we aimed to identify the functionally important miRNA species, which regulate apoptosis in CTCL....

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Detalhes bibliográficos
Main Authors: Manfè, Valentina, Biskup, Edyta, Rosbjerg, Anne, Kamstrup, Maria, Skov, Anne Guldhammer, Lerche, Catharina Margrethe, Lauenborg, Britt Thyssing, Ødum, Niels, Gniadecki, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250447/
https://ncbi.nlm.nih.gov/pubmed/22235305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029541
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