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miR-122 Regulates p53/Akt Signalling and the Chemotherapy-Induced Apoptosis in Cutaneous T-Cell Lymphoma

Advanced cutaneous T-cell lymphoma (CTCL) is resistant to chemotherapy and presents a major area of medical need. In view of the known role of microRNAs (miRNAs) in the regulation of cellular signalling, we aimed to identify the functionally important miRNA species, which regulate apoptosis in CTCL....

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Библиографические подробности
Главные авторы: Manfè, Valentina, Biskup, Edyta, Rosbjerg, Anne, Kamstrup, Maria, Skov, Anne Guldhammer, Lerche, Catharina Margrethe, Lauenborg, Britt Thyssing, Ødum, Niels, Gniadecki, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250447/
https://ncbi.nlm.nih.gov/pubmed/22235305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029541
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