Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma

Hypoxia contributes to the maintenance of stem-like cells in glioblastoma (GBM), and activates vascular mimicry and tumor resistance to anti-angiogenesis treatments. The present study examined the expression patterns and biological significance of hypoxia-inducible protein 2 (HIG2, also known as HIL...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mao, Xing-gang, Wang, Chao, Liu, Dong-ye, Zhang, Xiang, Wang, Liang, Yan, Ming, Zhang, Wei, Zhu, Jun, Li, Zi-chao, Mi, Chen, Tian, Jing-yang, Hou, Guang-dong, Miao, Si-yu, Song, Zi-xuan, Li, Jin-cheng, Xue, Xiao-yan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216980/
https://ncbi.nlm.nih.gov/pubmed/27329597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10029
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