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Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin

The Epidermal Growth Factor Receptor (EGFR) is centrally involved in the regulation of key processes of the epithelia, including cell proliferation, survival, differentiation, and also tumorigenesis. Humanized antibodies and small-molecule inhibitors targeting EGFR were developed to disrupt these fu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Lulli, Daniela, Carbone, Maria Luigia, Pastore, Saveria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216978/
https://ncbi.nlm.nih.gov/pubmed/27322144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10013
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