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Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin

The Epidermal Growth Factor Receptor (EGFR) is centrally involved in the regulation of key processes of the epithelia, including cell proliferation, survival, differentiation, and also tumorigenesis. Humanized antibodies and small-molecule inhibitors targeting EGFR were developed to disrupt these fu...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Lulli, Daniela, Carbone, Maria Luigia, Pastore, Saveria
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216978/
https://ncbi.nlm.nih.gov/pubmed/27322144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10013
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