MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy

MicroRNA-27a (miR-27a) upregulation has been identified in diabetes, but the pathogenesis of miR-27a in renal tubulointerstitial fibrosis (TIF) in diabetic nephropathy (DN) has not been elucidated. Herein, we found that high glucose stimulated miR-27a expression, which directly inhibited PPARγ and p...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Hou, Xiaoyan, Tian, Jianwei, Geng, Jian, Li, Xiao, Tang, Xun, Zhang, Jun, Bai, Xiaoyan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216977/
https://ncbi.nlm.nih.gov/pubmed/27351287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10283
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