MicroRNA-130b promotes lung cancer progression via PPARγ/VEGF-A/BCL-2-mediated suppression of apoptosis

BACKGROUND: The prognosis of non-small-cell lung cancer (NSCLC) is poor yet mechanistic understanding and therapeutic options remain limited. We investigated the biological and clinical significance of microRNA-130b and its relationship with apoptosis in NSCLC. METHODS: The level of microRNA-130b in...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Tian, Jianwei, Hu, Liping, Li, Xiao, Geng, Jian, Dai, Meng, Bai, Xiaoyan
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929777/
https://ncbi.nlm.nih.gov/pubmed/27364335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0382-3
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