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LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis
p53 is a major cellular tumor suppressor that in addition to its nuclear, transcription-dependent activity is also known to function extranuclearly. Cellular stressors such as reactive oxygen species can promote translocation of p53 into mitochondria where it acts to protect mitochondrial genome or...
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| Vydáno v: | Oncotarget |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216971/ https://ncbi.nlm.nih.gov/pubmed/27323408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9959 |
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