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LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis
p53 is a major cellular tumor suppressor that in addition to its nuclear, transcription-dependent activity is also known to function extranuclearly. Cellular stressors such as reactive oxygen species can promote translocation of p53 into mitochondria where it acts to protect mitochondrial genome or...
Sparad:
| I publikationen: | Oncotarget |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Impact Journals LLC
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216971/ https://ncbi.nlm.nih.gov/pubmed/27323408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9959 |
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