CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer

Chemokines and chemokine receptors are causally involved in the metastasis of human malignancies. As a crucial chemokine receptor for mediating immune homeostasis, however, the role of CCR4 in colorectal cancer (CRC) remains unknown. In this study, we found that high expression of CCR4 in CRC tissue...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ou, Baochi, Zhao, Jingkun, Guan, Shaopei, Feng, Hao, Wangpu, Xiongzhi, Zhu, Congcong, Zong, Yaping, Ma, Junjun, Sun, Jing, Shen, Xiaohui, Zheng, Minhua, Lu, Aiguo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216967/
https://ncbi.nlm.nih.gov/pubmed/27356745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10256
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