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CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer

Chemokines and chemokine receptors are causally involved in the metastasis of human malignancies. As a crucial chemokine receptor for mediating immune homeostasis, however, the role of CCR4 in colorectal cancer (CRC) remains unknown. In this study, we found that high expression of CCR4 in CRC tissue...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Ou, Baochi, Zhao, Jingkun, Guan, Shaopei, Feng, Hao, Wangpu, Xiongzhi, Zhu, Congcong, Zong, Yaping, Ma, Junjun, Sun, Jing, Shen, Xiaohui, Zheng, Minhua, Lu, Aiguo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216967/
https://ncbi.nlm.nih.gov/pubmed/27356745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10256
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