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FH535, a β-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis

The WNT/β-catenin pathway plays an important role in pancreatic cancer carcinogenesis. We evaluated the correlation between aberrant β-catenin pathway activation and the prognosis pancreatic cancer, and the potential of applying the β-catenin pathway inhibitor FH535 to pancreatic cancer treatment. M...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Lu, Zhi, Qiaoming, Shen, Meng, Gong, Fei-Ran, Zhou, Binhua P., Lian, Lian, Shen, Bairong, Chen, Kai, Duan, Weiming, Wu, Meng-Yao, Tao, Min, Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216931/
https://ncbi.nlm.nih.gov/pubmed/27323403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9975
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