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Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA

Cantharidin is an active constituent of mylabris, a traditional Chinese medicine, and is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays an important role in cell cycle control, apoptosis, and cell-fate determination. In the present study, we found that cantharidin repre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shen, Meng, Wu, Meng-Yao, Chen, Long-Pei, Zhi, Qiaoming, Gong, Fei-Ran, Chen, Kai, Li, Dao-Ming, Wu, Yadi, Tao, Min, Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488834/
https://ncbi.nlm.nih.gov/pubmed/26135631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11836
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