Augmentation of response to nab-paclitaxel by inhibition of insulin-like growth factor (IGF) signaling in preclinical pancreatic cancer models

Nab-paclitaxel has recently shown greater efficacy in pancreatic ductal adenocarcinoma (PDAC). Insulin like growth factor (IGF) signaling proteins are frequently overexpressed in PDAC and correlate with aggressive tumor phenotype and poor prognosis. We evaluated the improvement in nab-paclitaxel res...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Awasthi, Niranjan, Scire, Emily, Monahan, Sheena, Grojean, Meghan, Zhang, Eric, Schwarz, Margaret A., Schwarz, Roderich E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216918/
https://ncbi.nlm.nih.gov/pubmed/27127884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9029
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