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KLF4α stimulates breast cancer cell proliferation by acting as a KLF4 antagonist

Krüppel-like factor 4 (KLF4), a transcription factor involved in both tumor suppression and oncogenesis in various human tumors, is subject to alternative splicing that produces KLF4α. KLF4α is primarily expressed in the cytoplasm because it lacks exon 3 of KLF4, which contains the nuclear localizat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ferralli, Jacqueline, Chiquet-Ehrismann, Ruth, Degen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216746/
https://ncbi.nlm.nih.gov/pubmed/27323810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10058
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