MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4

BACKGROUND: Tumor metastasis is one of the leading causes of poor prognosis for colorectal cancer (CRC) patients. Loss of Smad4 contributes to aggression process in many human cancers. However, the underlying precise mechanism of aberrant Smad4 expression in CRC development is still little known. RE...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cheng, Dantong, Zhao, Senlin, Tang, Huamei, Zhang, Dongyuan, Sun, Hongcheng, Yu, Fudong, Jiang, Weiliang, Yue, Ben, Wang, Jingtao, Zhang, Meng, Yu, Yang, Liu, Xisheng, Sun, Xiaofeng, Zhou, Zongguang, Qin, Xuebin, Zhang, Xin, Yan, Dongwang, Wen, Yugang, Peng, Zhihai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216716/
https://ncbi.nlm.nih.gov/pubmed/27286257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9900
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