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Altered calcium influx of peripheral Th2 cells in pediatric Crohn's disease: infliximab may normalize activation patterns

OBJECTIVE: Crohn's disease is a chronic inflammation of the gastrointestinal tract with an abnormal immune phenotype. We investigated how intracellular calcium kinetics of Th1 and Th2 lymphocytes alter upon specific inhibition of Kv1.3 and IKCa1 channels in pediatric Crohn's disease. STUDY...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Orbán, Csaba, Szabó, Dolóresz, Bajnok, Anna, Vásárhelyi, Barna, Tulassay, Tivadar, Arató, András, Veres, Gábor, Toldi, Gergely
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216698/
https://ncbi.nlm.nih.gov/pubmed/27329601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10036
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