From the Cover: Manganese Stimulates Mitochondrial H(2)O(2) Production in SH-SY5Y Human Neuroblastoma Cells Over Physiologic as well as Toxicologic Range

Manganese (Mn) is an abundant redox-active metal with well-characterized mitochondrial accumulation and neurotoxicity due to excessive exposures. Mn is also an essential co-factor for the mitochondrial antioxidant protein, superoxide dismutase-2 (SOD2), and the range for adequate intake established...

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Sci
Hauptverfasser: Fernandes, Jolyn, Hao, Li, Bijli, Kaiser M., Chandler, Joshua D., Orr, Michael, Hu, Xin, Jones, Dean P., Go, Young-Mi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Manganese and Mitochondrial Hydrogen Peroxide Production
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216654/
https://ncbi.nlm.nih.gov/pubmed/27701121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw196
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