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A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe

One of the most frequent lesions formed in cellular DNA are abasic (apurinic/apyrimidinic, AP) sites that are both cytotoxic and mutagenic, and must be removed efficiently to maintain genetic stability. It is generally believed that the repair of AP sites is initiated by the AP endonucleases; howeve...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Alseth, Ingrun, Korvald, Hanne, Osman, Fekret, Seeberg, Erling, Bjørås, Magnar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC521664/
https://ncbi.nlm.nih.gov/pubmed/15452279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh851
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