DNA adopts normal B-form upon incorporation of highly fluorescent DNA base analogue tC: NMR structure and UV-Vis spectroscopy characterization

The influence of the highly fluorescent tricyclic cytosine base analogue (tC) on duplex DNA conformation is investigated. The duplex properties are characterized by absorbance and circular dichroism (CD) for all combinations of neighbouring bases to tC, and an NMR structure is determined for one tC-...

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Main Authors: Engman, K. Cecilia, Sandin, Peter, Osborne, Sadie, Brown, Tom, Billeter, Martin, Lincoln, Per, Nordén, Bengt, Albinsson, Bo, Wilhelmsson, L. Marcus
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC521657/
https://ncbi.nlm.nih.gov/pubmed/15452275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh844
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