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HEREDITARY, SPORADIC AND METASTATIC COLORECTAL CANCER ARE COMMONLY DRIVEN BY SPECIFIC SPECTRUMS OF DEFECTIVE DNA MISMATCH REPAIR COMPONENTS

DNA mismatch repair (MMR) is one of several human cell mechanisms utilized to repair mutable mistakes within DNA, particularly after DNA is replicated. MMR function is dependent upon heterodimerization of specific MMR proteins that can recognize base-base mispairs as well as frameshifts at microsate...

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Detalhes bibliográficos
Publicado no:Trans Am Clin Climatol Assoc
Autor principal: CARETHERS, JOHN M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Clinical and Climatological Association 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216503/
https://ncbi.nlm.nih.gov/pubmed/28066040
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