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Use of a Toxin Neutralization Assay To Characterize the Serologic Response to Adenylate Cyclase Toxin after Infection with Bordetella pertussis

Adenylate cyclase toxin (ACT) is an essential virulence factor of Bordetella pertussis, and antibodies to ACT protect against B. pertussis infection in mice. The toxin is therefore a strong candidate antigen for addition to future acellular pertussis vaccines. In order to characterize the functional...

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Publicado en:Clin Vaccine Immunol
Main Authors: Eby, Joshua C., Gray, Mary C., Warfel, Jason M., Merkel, Tod J., Hewlett, Erik L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216428/
https://ncbi.nlm.nih.gov/pubmed/27760780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00370-16
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