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A new hydrogen-bonding potential for the design of protein–RNA interactions predicts specific contacts and discriminates decoys

RNA-binding proteins play many essential roles in the regulation of gene expression in the cell. Despite the significant increase in the number of structures for RNA–protein complexes in the last few years, the molecular basis of specificity remains unclear even for the best-studied protein families...

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Detalhes bibliográficos
Main Authors: Chen, Yu, Kortemme, Tanja, Robertson, Tim, Baker, David, Varani, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521638/
https://ncbi.nlm.nih.gov/pubmed/15459285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh785
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