Angiopoietin-2 as a biomarker and target for immune checkpoint therapy

Immune checkpoint therapies targeting CTLA-4 and PD-1 have proven effective in cancer treatment. However, the identification of biomarkers for predicting clinical outcomes and mechanisms to overcome resistance remain as critical needs. Angiogenesis is increasingly appreciated as an immune modulator...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Wu, Xinqi, Giobbie-Hurder, Anita, Liao, Xiaoyun, Connelly, Courtney, Connolly, Erin M., Li, Jingjing, Manos, Michael P., Lawrence, Donald, McDermott, David, Severgnini, Mariano, Zhou, Jun, Gjini, Evisa, Lako, Ana, Lipschitz, Mikel, Pak, Christine J., Abdelrahman, Sara, Rodig, Scott, Hodi, F. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215959/
https://ncbi.nlm.nih.gov/pubmed/28003187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0206
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