Angiopoietin-2 as a biomarker and target for immune checkpoint therapy

Immune checkpoint therapies targeting CTLA-4 and PD-1 have proven effective in cancer treatment. However, the identification of biomarkers for predicting clinical outcomes and mechanisms to overcome resistance remain as critical needs. Angiogenesis is increasingly appreciated as an immune modulator...

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Gepubliceerd in:Cancer Immunol Res
Hoofdauteurs: Wu, Xinqi, Giobbie-Hurder, Anita, Liao, Xiaoyun, Connelly, Courtney, Connolly, Erin M., Li, Jingjing, Manos, Michael P., Lawrence, Donald, McDermott, David, Severgnini, Mariano, Zhou, Jun, Gjini, Evisa, Lako, Ana, Lipschitz, Mikel, Pak, Christine J., Abdelrahman, Sara, Rodig, Scott, Hodi, F. Stephen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215959/
https://ncbi.nlm.nih.gov/pubmed/28003187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0206
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