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Foxp3 and Toll-like receptor signaling balance T(reg) cell anabolic metabolism for suppression
CD4(+) effector T cells (T(eff) cells) and regulatory T cells (T(reg) cells) undergo metabolic reprogramming to support proliferation and immunological function. Although signaling via the lipid kinase PI(3)K (phosphatidylinositol-3-OH kinase), the serine-threonine kinase Akt and the metabolic check...
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Publicado no: | Nat Immunol |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215903/ https://ncbi.nlm.nih.gov/pubmed/27695003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3577 |
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