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Polymyxin Combinations: Pharmacokinetics and Pharmacodynamics for Rationale Use
Since their reintroduction into the clinic in the 1980s, the polymyxin antibiotics colistin—administered intravenously as an inactive prodrug, colistin methanesulfonate (CMS)—and polymyxin B have assumed an important role as salvage therapy for otherwise untreatable gram-negative infections. However...
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| Publié dans: | Pharmacotherapy |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215892/ https://ncbi.nlm.nih.gov/pubmed/25630411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1537 |
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