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Functionality and Robustness of Injured Connectomic Dynamics in C. elegans: Linking Behavioral Deficits to Neural Circuit Damage

Using a model for the dynamics of the full somatic nervous system of the nematode C. elegans, we address how biological network architectures and their functionality are degraded in the presence of focal axonal swellings (FAS) arising from neurodegenerative disease and/or traumatic brain injury. Usi...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Kunert, James M., Maia, Pedro D., Kutz, J. Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215891/
https://ncbi.nlm.nih.gov/pubmed/28056097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005261
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