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Roles of pRB in the Regulation of Nucleosome and Chromatin Structures

Retinoblastoma protein (pRB) interacts with E2F and other protein factors to play a pivotal role in regulating the expression of target genes that induce cell cycle arrest, apoptosis, and differentiation. pRB controls the local promoter activity and has the ability to change the structure of nucleos...

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Bibliographic Details
Published in:Biomed Res Int
Main Author: Uchida, Chiharu
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215604/
https://ncbi.nlm.nih.gov/pubmed/28101510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5959721
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