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Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure

In the last decade, indoleamine 2,3‐dioxygenase 1 (IDO1) has attracted a great deal of attention being recognized as key regulator of immunosuppressive pathways in the tumor immuno‐editing process. Several classes of inhibitors have been developed as potential anticancer agents, but only few of them...

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Detalhes bibliográficos
Publicado no:Mol Inform
Main Authors: Greco, Francesco Antonio, Bournique, Answald, Coletti, Alice, Custodi, Chiara, Dolciami, Daniela, Carotti, Andrea, Macchiarulo, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215573/
https://ncbi.nlm.nih.gov/pubmed/27546049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201501038
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