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Real‐time monitoring and control of the load phase of a protein A capture step
The load phase in preparative Protein A capture steps is commonly not controlled in real‐time. The load volume is generally based on an offline quantification of the monoclonal antibody (mAb) prior to loading and on a conservative column capacity determined by resin‐life time studies. While this res...
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| Pubblicato in: | Biotechnol Bioeng |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215519/ https://ncbi.nlm.nih.gov/pubmed/27543789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26078 |
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