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The Short Form of the Zinc Finger Antiviral Protein Inhibits Influenza A Virus Protein Expression and Is Antagonized by the Virus-Encoded NS1

Zinc finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses. There are two ZAP isoforms arising from alternative splicing, which differ only at the C termini. It was recently reported that the long isoform (ZAPL) promotes proteasomal degradation...

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Pubblicato in:J Virol
Autori principali: Tang, Qiannan, Wang, Xinlu, Gao, Guangxia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215320/
https://ncbi.nlm.nih.gov/pubmed/27807230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01909-16
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