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Can individualized sunitinib dose and schedule changes optimize outcomes for kidney cancer patients?

The recommended starting dose and schedule for sunitinib is 50 mg daily for 28 days, followed by a 14-day break with significant dose reductions to 37.5 mg (75% of starting dose), and then 25 mg (50% of starting dose) on the same schedule (four/two schedule). There are several reasons why these dose...

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Detalhes bibliográficos
Publicado no:Can Urol Assoc J
Autor principal: Bjarnason, Georg A.
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Medical Association 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215304/
https://ncbi.nlm.nih.gov/pubmed/28096939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5489/cuaj.4293
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