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Rapid Recall Ability of Memory T cells is Encoded in their Epigenome

Even though T-cell receptor (TCR) stimulation together with co-stimulation is sufficient for the activation of both naïve and memory T cells, the memory cells are capable of producing lineage specific cytokines much more rapidly than the naïve cells. The mechanisms behind this rapid recall response...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barski, Artem, Cuddapah, Suresh, Kartashov, Andrey V., Liu, Chong, Imamichi, Hiromi, Yang, Wenjing, Peng, Weiqun, Lane, H. Clifford, Zhao, Keji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215294/
https://ncbi.nlm.nih.gov/pubmed/28054639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39785
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