Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression

The mechanisms underlying diarrhea-predominant irritable bowel syndrome (IBS-D) are poorly understood, but increased intestinal permeability is thought to contribute to symptoms. A recent clinical trial of gluten-free diet (GFD) demonstrated symptomatic improvement, relative to gluten-containing die...

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Vydáno v:Lab Invest
Hlavní autoři: Wu, Richard Licheng, Vazquez-Roque, Maria, Carlson, Paula, Burton, Duane, Grover, Madhusudan, Camilleri, Michael, Turner, Jerrold R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215009/
https://ncbi.nlm.nih.gov/pubmed/27869798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.118
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