IFITM1 targets HIV-1 latently infected cells for antibody-dependent cytolysis

HIV-1 persistence in latent reservoirs during antiretroviral therapy (ART) is the main obstacle to virus eradication. To date, there is no marker that adequately identifies latently infected CD4(+) T cells in vivo. Using a well-established ex vivo model, we generated latently infected CD4(+) T cells...

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Vydáno v:JCI Insight
Hlavní autoři: Raposo, Rui André Saraiva, de Mulder Rougvie, Miguel, Paquin-Proulx, Dominic, Brailey, Phillip M., Cabido, Vinicius D., Zdinak, Paul M., Thomas, Allison S., Huang, Szu-han, Beckerle, Greta A., Jones, Richard B., Nixon, Douglas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214598/
https://ncbi.nlm.nih.gov/pubmed/28097226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85811
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