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NKG2D performs two functions in invariant NKT cells: Direct TCR-independent activation of NK-like cytolysis, and co-stimulation of activation by CD1d

Invariant NKT cells are important in the activation and regulation of immune responses. They can also function as CD1d-restricted killer cells. However, the role of activating innate NK cell receptors expressed on NKT cells in triggering cytolytic function is poorly characterized. Here, we initially...

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Hlavní autoři: Kuylenstierna, Carlotta, Björkström, Niklas K., Andersson, Sofia K., Sahlström, Peter, Bosnjak, Lidija, Paquin-Proulx, Dominic, Malmberg, Karl-Johan, Ljunggren, Hans-Gustaf, Moll, Markus, Sandberg, Johan K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523190/
https://ncbi.nlm.nih.gov/pubmed/21590763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940278
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