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Severe functional impairment and elevated PD-1 expression in the CD1d-restricted NKT cells retained in chronic HIV-1 infection

Invariant CD1d-restricted natural killer T (NKT) cells play important roles in regulating both innate and adaptive immunity. They are targeted by HIV-1 infection and severely reduced in number or even lost in many infected subjects. Here, we have investigated the characteristics of NKT cells retaine...

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Detalhes bibliográficos
Main Authors: Moll, Markus, Kuylenstierna, Carlotta, Gonzalez, Veronica D., Andersson, Sofia K., Bosnjak, Lidija, Sönnerborg, Anders, Quigley, Máire F., Sandberg, Johan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736548/
https://ncbi.nlm.nih.gov/pubmed/19197939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838780
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