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Cholinesterase-like domains in enzymes and structural proteins: functional and evolutionary relationships and identification of a catalytically essential aspartic acid.

Primary sequences of cholinesterases and related proteins have been systematically compared. The cholinesterase-like domain of these proteins, about 500 amino acids, may fulfill a catalytic and a structural function. We identified an aspartic acid residue that is conserved among esterases and lipase...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Krejci, E, Duval, N, Chatonnet, A, Vincens, P, Massoulié, J
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1991
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52145/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1862088/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.15.6647
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