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High-affinity binding sites for related fibroblast growth factor ligands reside within different receptor immunoglobulin-like domains.

Growth factors of the fibroblast growth factor (FGF) family bind receptors whose external domains are organized in a series of immunoglobulin-like loops. We engineered expression constructs in which cDNAs encoding individual immunoglobulin-like domains of the keratinocyte growth factor (KGF/FGF-7) r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cheon, H G, LaRochelle, W J, Bottaro, D P, Burgess, W H, Aaronson, S A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8302878/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.3.989
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