TRIM5α Promotes Ubiquitination of Rta from Epstein–Barr Virus to Attenuate Lytic Progression

Replication and transcription activator (Rta), a key protein expressed by Epstein–Barr virus (EBV) during the immediate-early stage of the lytic cycle, is responsible for the activation of viral lytic genes. In this study, GST-pulldown and coimmunoprecipitation assays showed that Rta interacts in vi...

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Vydáno v:Front Microbiol
Hlavní autoři: Huang, Hsiang-Hung, Chen, Chien-Sin, Wang, Wen-Hung, Hsu, Shih-Wei, Tsai, Hsiao-Han, Liu, Shih-Tung, Chang, Li-Kwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214253/
https://ncbi.nlm.nih.gov/pubmed/28105027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.02129
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