The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells

Programmed death-ligand 1 (PD-L1) is an inhibitory ligand that binds to PD-1 to suppress T cell activation. PD-L1 is constitutively expressed and inducible in tumor cells, but the expression profiles and regulatory mechanism of PD-L1 in myeloid-derived suppressor cells (MDSCs) are largely unknown. W...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Lu, Chunwan, Redd, Priscilla S., Lee, Jeffrey R., Savage, Natasha, Liu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214087/
https://ncbi.nlm.nih.gov/pubmed/28123883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1247135
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