Protection against Plasmodium falciparum malaria by PfSPZ Vaccine

BACKGROUND: A radiation-attenuated Plasmodium falciparum (Pf) sporozoite (SPZ) malaria vaccine, PfSPZ Vaccine, protected 6 of 6 subjects (100%) against homologous Pf (same strain as in the vaccine) controlled human malaria infection (CHMI) 3 weeks after 5 doses administered intravenously. The next s...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Epstein, Judith E., Paolino, Kristopher M., Richie, Thomas L., Sedegah, Martha, Singer, Alexandra, Ruben, Adam J., Chakravarty, Sumana, Stafford, April, Ruck, Richard C., Eappen, Abraham G., Li, Tao, Billingsley, Peter F., Manoj, Anita, Silva, Joana C., Moser, Kara, Nielsen, Robin, Tosh, Donna, Cicatelli, Susan, Ganeshan, Harini, Case, Jessica, Padilla, Debbie, Davidson, Silas, Garver, Lindsey, Saverino, Elizabeth, Murshedkar, Tooba, Gunasekera, Anusha, Twomey, Patrick S., Reyes, Sharina, Moon, James E., James, Eric R., KC, Natasha, Li, Minglin, Abot, Esteban, Belmonte, Arnel, Hauns, Kevin, Belmonte, Maria, Huang, Jun, Vasquez, Carlos, Remich, Shon, Carrington, Mary, Abebe, Yonas, Tillman, Amy, Hickey, Bradley, Regules, Jason, Villasante, Eileen, Sim, B. Kim Lee, Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214067/
https://ncbi.nlm.nih.gov/pubmed/28097230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89154
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