A Thioacetal Photocage Designed for Dual Release: Application in the Quantitation of Therapeutic Release via Synchronous Reporter Decaging

Despite the immense potential, application of existing photocaging technology is limited by the paucity of advanced caging tools. Here we report on the design of a novel thioacetal ortho-nitrobenzaldehyde (TNB) dual arm photocage that enables control of the simultaneous release of two payloads linke...

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Udgivet i:Chembiochem
Main Authors: Wong, Pamela T., Tang, Shengzhuang, Cannon, Jayme, Mukherjee, Jhindan, Isham, Danielle, Gam, Kristina, Payne, Michael, Yanik, Sean A., Baker, James R., Choi, Seok Ki
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213739/
https://ncbi.nlm.nih.gov/pubmed/27902870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600494
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