A Thioacetal Photocage Designed for Dual Release: Application in the Quantitation of Therapeutic Release via Synchronous Reporter Decaging

Despite the immense potential, application of existing photocaging technology is limited by the paucity of advanced caging tools. Here we report on the design of a novel thioacetal ortho-nitrobenzaldehyde (TNB) dual arm photocage that enables control of the simultaneous release of two payloads linke...

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Bibliographische Detailangaben
Veröffentlicht in:Chembiochem
Hauptverfasser: Wong, Pamela T., Tang, Shengzhuang, Cannon, Jayme, Mukherjee, Jhindan, Isham, Danielle, Gam, Kristina, Payne, Michael, Yanik, Sean A., Baker, James R., Choi, Seok Ki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5213739/
https://ncbi.nlm.nih.gov/pubmed/27902870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600494
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