B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

Occupancy of the T-cell receptor complex does not appear to be a sufficient stimulus to induce a T-cell-mediated immune response. Increasing evidence suggests that cognate cell-cell interaction between an activated T cell and an antigen-presenting cell may provide such a stimulus. A candidate T-cell...

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Bibliografiske detaljer
Main Authors: Gimmi, C D, Freeman, G J, Gribben, J G, Sugita, K, Freedman, A S, Morimoto, C, Nadler, L M
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52129/
https://ncbi.nlm.nih.gov/pubmed/1650475
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