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Identification of the (15)FRFG domain in HIV-1 Gag p6 essential for Vpr packaging into the virion

The auxiliary regulatory protein Vpr of HIV-1 is packaged in the virion through interaction with the Gag C-terminal p6 domain. Virion packaging of Vpr is critical for Vpr to exert functions in the HIV-1 life cycle. Previous studies suggest that Vpr interacts with a (Lxx)4 domain in p6 for virion pac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Henghu, Jian, Heng, Zhao, Ling-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC521086/
https://ncbi.nlm.nih.gov/pubmed/15363109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-1-26
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