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Heme oxygenase-2 gene deletion attenuates oxidative stress in neurons exposed to extracellular hemin

BACKGROUND: Hemin, the oxidized form of heme, accumulates in intracranial hematomas and is a potent oxidant. Growing evidence suggests that it contributes to delayed injury to surrounding tissue, and that this process is affected by the heme oxygenase enzymes. In a prior study, heme oxygenase-2 gene...

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Autori principali: Regan, Raymond F, Chen, Jing, Benvenisti-Zarom, Luna
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC521072/
https://ncbi.nlm.nih.gov/pubmed/15377391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-5-34
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